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The mechanism is purely metabolic: increased energy expenditure , suppressed lipogenesis, and elevated NAD+ levels that activate sirtuins (SIRT1, SIRT3), the same longevity-associated enzymes targeted by caloric restriction

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If a dose is missed, patients could apply it when remembered on the same day or resume the regular schedule at the next planned administration-double dosing is not recommended

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Mild soreness at the injection site is the most common report